The Race for a Vaccine. The Road to Demaskus

I dunno tbh

My feeling is that it doesn’t matter of it works if it calms the hysteria and brings back normality. Immhappy there is a vaccine, im not confident in it and I have reservations but its greatbwhat they have achieved. They gave be injecting people with saline and ill be happy. Covid is here to stay like the common cold, flu and aids. We have to live on but the biggest virus I see is the fear that has been drummed up. I genuinely hope these trials prove right in the general public when rolled out. I honestly didn’t think we would be at this point with a vaccine for several years a month ago. It was a great good news story that was shit upon by the zero covid lunatics and Nphet.

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The trial is based on half the group getting the vaccine and half a placebo. The results of the trial are based on the number of people who tested positive for Covid and what their outcome was. For the Pfizer trial, 90% of those who received the vaccine that tested positive had no symptoms, compared to the group who received a placebo.

What were the odds of them getting covid in the first place?

Is it like saying you have a vaccine for getting hit by a train because you gave it to 10,000 people and none of them got hit by a train?

It wouldn’t fill you with a lot of confidence, when you put it like that.

I’m sure there’s more science behind it than that

The vaccine is for the fear as much as anything.

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Similar odds to the general public I would imagine, the preliminary results were based on about 100 who tested positive out of 40k participants.

That’s what I was wondering? What is the average person’s chance of catching covid 19

Based on cases about a few %? 13 million have tested positive in the US so that’s close to 4%. But that’s over most of a year by now.

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Lads, he’s cracked it. Take him down.

As explained elsewhere

There are two lots of people one gets the vaccine one doesn’t. For easy maths let’s say 20k in each group. Obviously not all of these have been exposed to covid yet or caught covid. But the cases are ten times less in the group that had the vaccine than in the group that didn’t have the vaccine.

Even at very small numbers of infections it’s statistically significant enough to draw conclusions. They have to hit a certain number of people infected in the other group before they move on from level three trials and as the move onto the next phase this phase would continue to be monitored. By the end of their studies etc. I think anything above 70% effective would be considered a success. WHO said 50% would do earlier in the process

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During the trials they gave them the vaccine and ushered them back under the bed.

Yeah obviously with positivity rates of between 3 and 5pc this obviously doesn’t mean 3pc of people have covid it’s 3pc of people with symptoms or who have been close contacts of confirmed cases. That’s low enough when you think about it. If they took 1000 people in a controlled but random way like they’d choose them for a poll or survey how many would have it I wonder. Has anyone done this?

I have a vaccine that will save you if you get hit by a train and if I doesn’t work I’ll give you your money back.

The ones who get hit by a train have just had an adverse reaction to the vaccine.

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Reactogenicity will be buzzword in 2021.

https://science.sciencemag.org/content/370/6520/1022.full

You’d swear listening to your man Brendan o Connor on the radio there is no hope of safely vaccinating people in Ireland. As @Tassotti says paddy has a problem for every solution.

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